Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption.
نویسندگان
چکیده
Five healthy volunteers and six patients with Parkinson's disease (PD) ate 250 g cooked broad beans after 12 hours without treatment. During the next four hours a substantial clinical improvement was noted, three patients showed severe dyskinesias, and plasma levodopa concentrations rose.
منابع مشابه
Broad bean (Vicia faba) consumption and Parkinson's disease.
In 1913, Guggenheim identified L-DOPA in the seedlings, pods, and beans of the broad bean, Vicia faba (VF). Since then, anecdotal cases of symptomatic improvement after VF consumption have been described in patients with PD. In the present study, five healthy volunteers and six PD patients (mean age, 63.5 years; mean disease duration, 13 years; stage III, Hoehn-Yahr scale) ate 250 g cooked VF a...
متن کاملBroad bean (Vicia faba) consumption and Parkinson's disease: a natural source of L-dopa to consider.
ଝ Consumo de habas (Vicia faba) y enfermedad de Parkinson: una fuente natural de L-dopa a tener en cuenta Dear Editor: Scientists know that broad beans (Vicia faba) contain enough L-dopa to be pharmacologically active on patients with Parkinson's disease (PD). It has been shown that these beans increase plasma levels of L-dopa and improve motor function. 1 We present the case of a patient with ...
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The effect of low pH on net H(+) release and root growth of corn (Zea mays L.) and broad bean (Vicia faba L.) seedlings was investigated in short-term experiments at constant pH. Broad bean was more sensitive to low pH than corn: the critical values (pH values below which net H(+) release and root growth ceased) were pH 4.00 (broad bean) and pH 3.50 (corn) at 1 millimolar Ca(2+). Both proton re...
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consumption of broad beans, plasma levodopa levels remain at higher levels for longer periods in patients than in healthy volunteers. This is probably caused by the potent longterm effect of carbidopa on peripheral decarboxylase. The increase in plasma levodopa in PD patients after broad bean consumption is accompanied by significant improvement in motor symptoms; in some cases, intense dyskine...
متن کاملModifications in plasma cholesterol and apolipoproteins of hypercholesterolaemic rats induced by ethanol-soluble factors of Vicia faba.
High-fat-high-cholesterol diets containing casein or a Vicia faba bean (faba bean) protein concentrate as the protein source were given to rats for 5 weeks. When the faba bean protein concentrate or its ethanol extract was present in the diet, a marked decrease was found in the level of circulating cholesterol associated with the lower-density lipoproteins (very-low-, intermediate- and low-dens...
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 55 8 شماره
صفحات -
تاریخ انتشار 1992